Eagles vs. 49ers Prediction and Betting Pick

Conference Finals, Eagles, 49ers, Championship, Superbowl, Trophy

Only two teams from the NFC remain in contention to win Super Bowl 57. The 49ers will travel to Philadelphia and take on the Eagles. These are the top two remaining seeds in the conference. Both teams have also won at least nine of their previous 11 games.

It should be a cracking match, and the latest odds prove it. I explore the Eagles vs. 49ers betting lines and share my predictions in this article. Both the 49ers and the Eagles look unbeatable at the moment, but there can be only one winner!

If you want info on the AFC Conference final, we have a similar betting preview you can visit.

Eagles vs. 49ers Betting Odds and Lines

  • San Francisco 49ers; +128
  • Philadelphia Eagles; -148
  • 49ers (+2.5); -103
  • Eagles (-2.5); -117
  • Over 46; -110
  • Under 46; -110

These two teams have dominated the NFC and are now meeting each other in the conference title game. Philadelphia holds a small advantage over San Francisco in the early Eagles vs. 49ers betting odds. However, both teams are pretty evenly matched.


The main difference here is the experience at quarterback. The Eagles have QB Jalen Hurts leading the charge – a third-year player who’s an MVP candidate this season. Brock Purdy is in his rookie season but defying expectations (he’s 7-0 in seven career starts).

Let’s take a deeper look at both sides and try to figure out who has the upper hand.

Philadelphia Eagles

  • Regular-Season Record: 14-3
  • Head Coach: Nick Sirianni
  • Key Players: Jalen Hurts, AJ Brown, DeVonta Smith, Miles Sanders
  • NFC Titles: 2

It’s been five years since the Eagles appeared in the NFC Championship game. That was also the same season that Philadelphia won a Super Bowl for the first time in franchise history. The Eagles have also been the most preeminent team in the NFC this season.

Many bettors are going to choose Philadelphia with their Eagles vs. 49ers prediction. They’ve dominated the competition throughout the regular season. The defense has been good, and the offense has been virtually unstoppable.

The only major concern surrounding Philadelphia is QB Jalen Hurts’ health status. He suffered a shoulder sprain in Week 15 and missed two games during the regular season. Philadelphia went 0-2 during that stretch in which Hurts was inactive.

During the Divisional Round of the playoffs, the Eagles looked incredibly well-balanced. The offense was explosive against New York, amassing 416 total yards. Both Miles Sanders and Kenneth Gainwell rushed for more than 90 yards.

The deadly receiving trio of AJ Brown, DeVonta Smith, and Dallas Goedert deserve attention too. When these three players are healthy, the Eagles offense is extremely potent. Both Brown and Smith combined for 2,692 yards during the regular season, which is pretty insane.

I also want to discuss the defense, which is well above average. The defensive line is as good as it gets in the NFL, having also dominated the Giants during the Divisional Round. The Eagles came away with five sacks on QB Daniel Jones and limited the Giants to 227 total yards.

This is a well-rounded team with top players on both ends. It’s hard to see the Eagles going home yet, but their opponents are strong too.

San Francisco 49ers

  • Regular-Season Record: 13-4
  • Head Coach: Kyle Shanahan
  • Key Players: Brock Purdy, Christian McCaffrey, George Kittle, Fred Warner
  • NFC Titles: 7

What San Francisco has been able to do with a rookie starting QB is simply mind-boggling. The 49ers are also entering their match against the Eagles, having won their previous 12 games. This will be San Francisco’s third appearance in the NFC Championship in four years.

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Head coach Kyle Shanahan could also advance to the Super Bowl for the third time in his career. He has a 6-2 playoff record, and he’s coaching one of the hottest teams in the NFL right now. His model for success is something that can’t be understated.

Your NFC Championship Game prediction should also consider the 49ers’ dominance since late October. During the team’s current win streak, San Francisco has held its opponents to 17 points or less in nine games. The defense is scary good right now, and that’s what wins titles!

The 49ers’ greatest defensive effort this season also took place during the Divisional Round. The team forced multiple interceptions and held Dallas to just 282 yards of offense. This was just a week after the Cowboys ran up the score against the Buccaneers.

The offense is also pretty potent for the 49ers. The team put all of its trust in rookie QB Brock Purdy, who was the final selection of the 2022 NFL Draft (i.e., Mr. Irrelevant). And yet, looks like a veteran player who seemingly thrives under pressure.

Purdy also benefits from having a strong supporting cast around him. His best weapons include Christian McCaffrey, George Kittle, and Deebo Samuel. These are three dynamic athletes who can rack up yards and make plenty of big plays.

NFC Championship Game 2023 Prediction and Betting Pick

Before I offer you my Eagles vs. 49ers betting pick and prediction, let’s do a quick recap. San Francisco enters the game as an underdog against Philadelphia. However, these two teams are the biggest juggernauts in the NFL right now.


The 49ers boast a top-five defense overall, but the Eagles rank second-best in yards allowed. Philadelphia also had the No. 3 scoring offense from the regular season, giving them a slight edge over San Francisco.

The Eagles’ biggest weakness is defending the run. The team allows an average of 4.6 yards per carry against opposing offenses. I think the 49ers can win this game if they can get creative with how they use McCaffrey and the other running backs.

Ultimately, I’m picking San Francisco with my Eagles vs. 49ers prediction. All they have to do is run the ball and limit the big plays from Jalen Hurts. The Eagles’ offense is pretty dangerous, but the 49ers are the more well-rounded team.

Jim Beviglia
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About Jim Beviglia
Jim Beviglia has been a gambling writer at LegitGamblingSites.com since 2018. During that time, he’s written just about every type of article related to gambling, including reviews of betting sites, guides to popular casino games, betting tips on both casino and sports betting, sports and casino blog posts, and game picks. In addition to online gambling, one of Jim’s other major interests is music. He has been doing freelance work for various music sites and magazines for two decades. Among his outlets past and present are American Songwriter, VinylMePlease, Treble, and The Bluegrass Situation. Jim has also written five books on music that were published by Rowman & Littlefield.